PUBLICATIONS (Google Scholar Profile):
Preprints not yet peer reviewed / published:
L. T. Yu, M. A. B. Kreutzberger, M. C. Hancu, T. H. Bui, A. C. Farsheed, E. H. Egelman, J. D. Hartgerink "Beyond the Triple Helix: Exploration of the Hierarchical Assembly Space of Collagen-like Peptides" bioRxiv 2024.05.14.594194. DOI: 10.1101/2024.05.14.594194
E. M. Euliano, B. H. Pogostin, A. Agrawal, M. H. Yu, T. H. Baryakova, T. P. Graf, J. D. Hartgerink, K. J. McHugh "A TLR7 Agonist Conjugated to a Nanofibrous Peptide Hydrogel as a Potent Vaccine Adjuvant" bioRxiv 2024.03.07.583938. DOI: 10.1101/2024.03.07.583938
B. H. Pogostin, S. X. Wu, M. J. Swierczynski, C. Pennington, S. Li, D. Vohidova, E. H. Seeley, A. Agrawal, C. Tang, J. Cabler, A. Dey, O. Veiseh, E. L. Nuermberger, Z. T. Ball, J. D. Hartgerink, K. J. McHugh "Enhanced dynamic covalent chemistry for the controlled release of small molecules and biologics from a nanofibrous peptide hydrogel platform" bioRxiv 2024.05.21.595134. DOI: 10.1101/2024.05.21.595134
Published & Peer Reviewed work:
2024
C.C. Cole, D.R. Walker, S.A.H. Hulgan, B.H. Pogostin, J.W.R. Swain, M.D. Miller, W. Xu, R. Duella, M. Misiura, X. Wang, A.B. Kolomeisky, G.N. Phillips Jr., and J.D. Hartgerink "Heterotrimeric Collagen Helix with High Specificity of Assembly Results in a Rapid Rate of Folding" 2024, Nature Chemistry, available online. DOI: 10.1038/s41557-024-01573-2.
A. Farsheed, C. Zevallos-Delgado, L. T. Yu, S. Saeidifard, J. Swain, J. Makhoul, A. Thomas, C. Cole, E. Garcia Huitron, K. J. Grande-Allen, M. Singh, K. V. Larin, J. D. Hartgerink "Tunable Macroscopic Alignment of Self-Assembling Peptide Nanofibers" ACS Nano 2024, 18, 19, 12477-12488. DOI: 10.1021/acsnano.4c02030
M. P. Dong, N. Dharmaraj, E. Kaminagakura, J. Xue, D. G. Leach, J. D. Hartgerink, M. Zhang, H. Hanks, Y. Ye, B. E. Aouizerat, K. Vining, C. M. Thomas, S. Dovat, S. Young and C. T. Viet "Stimulator of Interferon Genes Pathway Activation through the Controlled Release of STINGel Mediates Analgesia and Anti-Cancer Effects in Oral Squamous Cell Carcinoma" Biomedicines 2024, 12, 920. DOI: 10.3390/biomedicines12040920
V. Leyva-Aranda, S. Singh, M. Telesforo, S. Young, C. Yee, J. D. Hartgerink, "Nanofibrous MultiDomain Peptide hydrogels provide T cells a 3D, cytocompatible environment for cell expansion and antigen specific killing" ACS Biomaterials Science & Engineering 2024, 10, 3, 1448-1460. DOI: 10.1021/acsbiomaterials.3c01617
2023
C. Cole, L. T. Yu, M. Misiura, J. Williams III, T. Bui, J. D. Hartgerink "Stabilization of Synthetic Collagen Triple Helices: Charge Pairs and Covalent Capture" Biomacromolecules 2023, 24, 11, 5083–5090. DOI: 10.1021/acs.biomac.3c00680
J. W. R. Swain, C. Y. Yang, and J. D. Hartgerink "Orthogonal Self-Assembly of Amphiphilic Peptide Hydrogels and Liposomes Results in Composite Materials with Tunable Release Profiles" Biomacromolecules 2023, 24, 11, 5018–5026. DOI: 10.1021/acs.biomac.3c00664
A. Hernandez, J. D. Hartgerink, S. Young "Self-assembling peptides as immunomodulatory biomaterials" Front. Bioeng. Biotechnol. 2023, 11:1139782. DOI: 10.3389/fbioe.2023.1139782
L. T. Yu, M. C. Hancu, M. A. B. Kreutzberger, A. Henrickson, B. Demeler, E. H. Egelman, J. D. Hartgerink "Hollow Octadecameric Self-Assembly of Collagen-like Peptides" J. Am. Chem. Soc. 2023 145, 9, 5285–5296. DOI: 10.1021/jacs.2c12931
A. C. Farsheed, A. J. Thomas, B. H. Pogostin, J. D. Hartgerink "3D Printing of Self-assembling Nanofibrous Multidomain Peptide Hydrogels" Adv. Mater. 2023, 2210378. DOI: 10.1002/adma.202210378
B. H. Pogostin, G. Saenz, C. Cole, E. Euliano, J. D. Hartgerink, K. McHugh "Dynamic Imine Bonding Facilitates Mannan Release from a Nanofibrous Peptide Hydrogel" Bioconjugate Chem. 2023, 34, 1, 193–203 DOI: 10.1021/acs.bioconjchem.2c00461
H. A. Pearce, J. W. R. Swain, L. H. Victor, K. J. Hogan, E. Y. Jiang, M. L. Bedell, A. M. Navara, A. Farsheed, Y. S. Kim, J. L. Guo, J. D. Hartgerink, K. J. Grande-Allen, A. G. Mikos "Thermogelling hydrogel charge and lower critical solution temperature influence cellular infiltration and tissue integration in an ex vivo cartilage explant model" J. Biomed. Mater. Res. 2023, 1, 15-34. DOI: 10.1002/jbm.a.37441
R. P. Shupak, J. Hartgerink, C. S. E. Lai, S. Young, A. M. Linnebur, Z. S. Peacock, S. R. Chandra, A. Patel and J. C. Melville "Trigeminal Nerve Reconstruction in Maxillofacial Surgery" In: Melville, J.C., Coelho, P.G., Young, S. (eds) Advancements and Innovations in OMFS, ENT, and Facial Plastic Surgery. Springer, Cham. 2023. DOI: 10.1007/978-3-031-32099-6_19
G. M. Sunga, J. Hartgerink, A. G. Sikora, and S. Young "Enhancement of Immunotherapies in Head and Neck Cancers Using Biomaterial-Based Treatment Strategies" Tissue Engineering Part C: Methods 2023, 29:6, 257-275. DOI: 10.1089/ten.tec.2023.0090
A. Hernandez, J. D. Hartgerink, S. Young "Self-assembling peptides as immunomodulatory biomaterials" Front. Bioeng. Biotechnol. 2023 11:1139782. DOI: 10.3389/fbioe.2023.1139782.
2022
C. C. Cole, M. Misiura, S. A. H. Hulgan, C. M. Peterson, J. W. Williams III, A. B. Kolomeisky, J. D. Hartgerink "Cation-π Interactions and their Role in Assembling Collagen Triple Helices" Biomacromolecules 2022, 23, 11 4645-4654. DOI: 10.1021/acs.biomac.2c00856
B. H. Pogostin, M. H. Yu, A. R. Azares, E. M. Euliano, C. S. E. Lai, G. Saenz, S. X. Wu, A. C. Farsheed, S. M. Melhorn, T. P. Graf, D. G. Woodside, J. D. Hartgerink, K. J. McHugh "Multidomain peptide hydrogel adjuvants elicit strong bias towards humoral immunity" Biomater. Sci. 2022, 10, 6217-6229. DOI: 10.1039/D2BM01242A
C. S. E. Lai, V. Leyva-Aranda, V. H. Kong, T. L. Lopez-Silva, A. C. Farsheed, C. D. Cristobal, J. W. R. Swain, H. K. Lee, J. D. Hartgerink "A Combined Conduit-Bioactive Hydrogel Approach for Regeneration of Transected Sciatic Nerves" ACS Applied Bio Materials 2022, 5, 10, 4611-4624. DOI: 10.1021/acsabm.2c00132
J. C. Chen, P. Kan, Z. Yu, F. Alrashdan, R. Garcia, A. Singer, C. S. E. Lai, B. Avants, S. Crosby, Z. Li, B. Wang, M. M. Felicella, A. Robledo, A. V. Peterchev, S. M. Goetz, J. D. Hartgerink, S. A. Sheth, K. Yang, J. T. Robinson "A wireless millimetric magnetoelectric implant for the endovascular stimulation of peripheral nerves" Nature Biomedical Engineering 2022, 6, 706–716. DOI: 10.1038/s41551-022-00873-7
C. M. Peterson, M. R. Helterbrand, J. D. Hartgerink "Covalent Capture of a Collagen Mimetic Peptide with an Integrin Binding Motif" Biomacromolecules 2022, 23, 6, 2396-2403. DOI: 10.1021/acs.biomac.2c00155
S. A. H. Hulgan, J. D. Hartgerink "Recent Advances in Collagen Mimetic Peptide Structure and Design" Biomacromolecules 2022, 23, 4, 1475-1489. DOI: 10.1021/acs.biomac.2c00028.
L. T. Yu, J. D. Hartgerink "Selective Covalent Capture of Collagen Triple Helices with a Minimal Protecting Group Strategy" Chemical Science 2022, 13, 2789-2796. DOI: 10.1039/D1SC06361H
2021
H. A Pearce, E. Y. Jiang, J. W. R. Swain, A. M. Navara, J. L. Guo, Y. S. Kim, A. Woehr, J. D. Hartgerink, A. G. Mikos "Evaluating the physicochemical effects of conjugating peptides into thermogelling hydrogels for regenerative biomaterials applications" Regenerative Biomaterials 2021, 8, 6, rbab073. DOI: 10.1093/rb/rbab073.
D. R. Walker, A. A. Alizadehmojarad, A. Kolomeisky, J. D. Hartgerink "Charge-free, stabilizing amide-π interactions can be used to control collagen triple helix self-assembly" Biomacromolecules 2021 22, 5, 2137-2147. DOI: 10.1021/acs.biomac.1c00234.
D. R. Walker, S. A. Hulgan, C. M. Peterson, I. Li, K. J. Gonzalez, J. D. Hartgerink "Predicting the stability of homotrimeric and heterotrimeric collagen helices" Nature Chem. 2021 13, 260-269. DOI: 10.1038/s41557-020-00626-6.
Y. Shi, T. Xie, D. G Leach, B. Wang, S. Young, A. A. Osman, A. G. Sikora, X. Ren, J. D. Hartgerink, J. N. Myers, R. Rangel “Local anti-PD-1 delivery prevents progression of premalignant lesions in a 4NQO-oral carcinogenesis mouse model” Cancer Prevention Res. 2021, 14, 8, 767-777. DOI: 10.1158/1940-6207.CAPR-20-0607.
D. G. Leach, N. Dharmaraj, T. L. Lopez-Silva, J. R. Venzor, B. H. Pogostin, A. G. Sikora, J. D. Hartgerink, S. Young "Biomaterial-Facilitated Immunotherapy for Established Oral Cancers" ACS Biomaterials Sci. Eng. 2021, 7, 2, 415-421. DOI: 10.1021/acsbiomaterials.0c01575.
N. M. Muñoz, M. Williams, K. Dixon, C. Dupuis, A. McWatters, R. Avritscher, S. Z. Manrique, K. McHugh, R. Murthy, A. Tam, A. Naing, S. P. Patel , D. Leach, J. D. Hartgerink, S. Young, P. Prakash, P. Hwu, R. A. Sheth "Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy" J. ImmunoTherapy Cancer 2021, 9, e001800. DOI: 10.1136/jitc-2020-001800.
Y. Shi, T. Xie, D. G. Leach, B. Wang, S. Young, A. A. Osman, A. G. Sikora, X. Ren, J. D. Hartgerink, J. N. Myers, R. Rangel "Local anti-PD-1 delivery prevents progression of premalignant lesions in a 4NQO-oral carcinogenesis mouse model" Cancer Prev. Res. 2021, 14, 767-768. DOI: 10.1158/1940-6207.CAPR-20-0607.
T. L. Lopez-Silva, C. D. Cristobal, C. S. E. Lai, V. Leyva-Aranda, H. K. Lee, J. D. Hartgerink "Self-assembling Multidomain Peptide Hydrogels accelerate Peripheral Nerve Regeneration after Crush Injury" Biomaterials 2021, 265, 120401. DOI: 10.1016/j.biomaterials.2020.120401. (This publication was made available online in its final form in September 2020 but was organized for the January 2021 issue of Biomaterials.)
2020
S. A. H. Hulgan, A. A. Jalan, I. Li, D. R. Walker, M. D. Miller, A. J. Kosgei, W. Xu, G. N. Phillips, J. D. Hartgerink "Covalent Capture of Collagen Triple Helices using Lysine-Aspartate and Lysine-Glutamate Pairs" Biomacromolecules 2020, 21, 3772−3781. DOI: 10.1021/acs.biomac.0c00878.
A. A. Jalan, D. Sammon, J. D. Hartgerink, P. Brear, K. Stott, S. W. Hamaia, E. J. Hunter, D. R. Walker, B. Leitinger and R. W. Farndale “Chain alignment of collagen I deciphered using computationally designed heterotrimers” Nature Chem. Biol. 2020, 16, 423-429. DOI: 10.1038/s41589-019-0435-y.
T. L. Lopez-Silva, D. G. Leach, A. Azares, I. Li, D. G. Woodside, J. D. Hartgerink “Chemical functionality of multidomain peptide hydrogels governs early host T immune response” Biomaterials 2020, 231, 119667. DOI: 10.1016/j.biomaterials.2019.119667.
2019
D. G. Leach, J. M. Newton, M. A. Florez, T. L. Lopez-Silva, A. A. Jones, S. Young, A. G. Sikora, and J. D. Hartgerink “Drug-Mimicking Nanofibrous Peptide Hydrogel for Inhibition of Inducible Nitric Oxide Synthase” ACS Biomater. Sci. Eng. 2019, 5, 6755-6765. DOI: 10.1021/acsbiomaterials.9b01447.
I. Li, S. A. H. Hulgan, D. R. Walker, R. W. Farndale, J. D. Hartgerink, and A. A. Jalan “Covalent Capture of a Heterotrimeric Collagen Helix” Org. Lett. 2019, 21, 5480-5484. DOI: 10.1021/acs.orglett.9b01771.
D. G. Leach, S. Young, J. D. Hartgerink “Advances in immunotherapy delivery from implantable and injectable biomaterials” Acta Biomaterialia 2019, 88, 15-31. DOI: 10.1016/j.actbio.2019.02.016.
T. L. Lopez-Silva, D. G. Leach, I. Li, X. Wang, J. D. Hartgerink “Self-Assembling Multidomain Peptides: Design and Characterization of Neutral Peptide-Based Materials with pH and Ionic Strength Independent Self-Assembly” ACS Biomaterials Sci. Eng. 2019, 5, 977-985. DOI: 10.1021/acsbiomaterials.8b01348.
2018
N. C. Carrejo, A. N. Moore, T. L. Lopez Silva, D. G. Leach, I. Li, D. R. Walker, J. D. Hartgerink “Multidomain Peptide Hydrogel Accelerates Healing of Full-Thickness Wounds in Diabetic Mice” ACS Biomaterials Sci. Eng. 2018, 4, 1386-1396. DOI: 10.1021/acsbiomaterials.8b00031.
D. G. Leach, N. Dharmaraj, S. L. Piotrowski, T. L. Lopez-Silva, Y. Lei, A. G. Sikora, S. Young and J. D. Hartgerink “STINGel: Controlled Release of a Cyclic Dinucleotide for Enhanced Cancer Immunotherapy” Biomaterials 2018, 163, 67-75. DOI: 10.1016/j.biomaterials.2018.01.035.
A. N. Moore, T. L. Lopez Silva, N. C. Carrejo, C. A. Marmolejo Origel, I. Li and J. D. Hartgerink “Nanofibrous Peptide Hydrogel Elicits Angiogenesis and Neurogenesis without Drugs, Proteins, or Cells” Biomaterials 2018, 161, 154-163. DOI: 10.1016/j.biomaterials.2018.01.033.
2017
I. Li and J. D. Hartgerink “Covalent Capture of Aligned Self-Assembling Nanofibers” J. Am. Chem. Soc., 2017, 139, 8044–8050. DOI: 10.1021/jacs.7b04655.
A. M. Acevedo-Jake, D. H. Ngo and J. D. Hartgerink “Control of Collagen Triple Helix Stability by Phosphorylation” Biomacromolecules 2017, 18, 1157-1161. DOI: 10.1021/acs.biomac.6b01814.
A. N. Moore and J. D. Hartgerink “Self-Assembling Multidomain Peptide Nanofibers for Delivery of Bioactive Molecules and Tissue Regeneration” Acc. Chem. Res. 2017, 50, 714-722. DOI: 10.1021/acs.accounts.6b00553.
K. A. Clements, A. M. Acevedo-Jake, D. R. Walker and J. D. Hartgerink “Glycine Substitutions in Collagen Heterotrimers Alter Triple Helical Assembly” Biomacromolecules 2017, 18, 617-624. DOI: 10.1021/acs.biomac.6b01808.
2016
I. Li, A. N. Moore and J. D. Hartgerink, “Missing Tooth Multidomain Peptide Nanofibers for Delivery of Small Molecule Drugs” Biomacromolecules 2016, 17 (6) 2087 - 2095. DOI: 10.1021/acs.biomac.6b00309.
V. A. Kumar , Q. Liu , N. C Wickremasinghe , S. Shi , T. T. Cornwright , Y. Deng, A. Azares, A. N Moore, A. M. Acevedo-Jake, N. Agudo, S. Pan, D. G. Woodside, P. Vanderslice, J. T. Willerson, R. A. Dixon, J. D. Hartgerink “Treatment of hind limb ischemia using angiogenic peptide nanofibers” Biomaterials 2016, 98, 113-119. DOI: 10.1016/j.biomaterials.2016.04.032.
A. M. Acevedo-Jake, K. A. Clements, and Jeffrey D. Hartgerink “Synthetic, Register-Specific, AAB Heterotrimers to Investigate Single Point Glycine Mutations in Osteogenesis Imperfecta” Biomacromolecules 2016, 17, 914-921. DOI: 10.1021/acs.biomac.5b01562.
2015
V. A. Kumar, N. C. Wickremasinghe, S. Shi, and J. D. Hartgerink “Nanofibrous Snake Venom Hemostat” ACS Biomaterials Sci. Eng. 2015, 1, 1300-1305. DOI: 10.1021/acsbiomaterials.5b00356.
N. C. Wickremasinghe, V. A. Kumar, S. Shi, and J. D. Hartgerink "Controlled Angiogenesis in Peptide Nanofiber Composite Hydrogels" ACS Biomaterials Sci. Eng. 2015, 1, 845-854. DOI: 10.1021/acsbiomaterials.5b00210.
A. Moore, S. C. Perez, J. D. Hartgerink, R. N. D'Souza, and J. Colombo "Ex Vivo Modeling of Multidomain Peptide Hydrogels with Intact Dental Pulp" J. Dental Res. 2015, 94, 12, 1773-1781. DOI: 10.1177/0022034515600380.
V. A. Kumar, N. L. Taylor, S. Shi, N. C. Wickremasinghe, R. N. D'Souza and J. D. Hartgerink "Self-assembling multidomain peptides tailor biological responses through biphasic release" Biomaterials 2015, 52, 71-78. DOI: 10.1016/j.biomaterials.2015.01.079.
V. A. Kumar, S. Shi, B. K. Wang, I. Li, A. A. Jalan, B. Sarkar, N. C. Wickremasinghe and J. D. Hartgerink, "Drug-Triggered and Cross-Linked Self-Assembling Nanofibrous Hydrogels" J. Am. Chem. Soc. 2015, 137 4823-4830. DOI: 10.1021/jacs.5b01549.
V. A. Kumar, N. L. Taylor, S. Shi, B. K. Wang, A. A. Jalan, M. K. Kang, N. C. Wickremasinghe, J. D. Hartgerink “Highly Angiogenic Peptide Nanofibers” ACS Nano, 2015, 9, 860-868. DOI: 10.1021/nn506544b.
A. M. Acevedo-Jake, A. A. Jalan, J. D. Hartgerink “Comparative NMR Analysis of Collagen Triple Helix Organization from N- to C-Termini” Biomacromolecules, 2015, 16, 145-155. DOI: 10.1021/bm501281a.
2014
B. Sarkar, L. E. R. O’Leary, J. D. Hartgerink “Self-Assembly of Fiber-Forming Collagen Mimetic Peptides Controlled by Triple-Helical Nucleation” J. Am. Chem. Soc., 2014, 136, 14417-14424. DOI: 10.1021/ja504377s.
N. C. Wickremasinghe, V. A. Kumar, J. D. Hartgerink “Two-Step Self-Assembly of Liposome-Multidomain Peptide Nanofiber Hydrogel for Time-Controlled Release” Biomacromolecules, 2014 15, 3587-3595. DOI: 10.1021/bm500856c.
J. S. Colombo, A. N. Moore, J. D. Hartgerink, R. N. D’Souza “Scaffolds to Control Inflammation and Facilitate Dental Pulp Regeneration” J. Endodontics, 2014, 40, S6-S12. DOI: 10.1016/j.joen.2014.01.019.
A. A. Jalan, K. A. Jochim, J. D. Hartgerink “Rational Design of a Non-canonical “Sticky-ended” ABC-Collagen Triple Helix” J. Am. Chem. Soc., 2014, 136, 7535-7538. DOI: 10.1021/ja5001246.
M. K. Kang, J. Colombo, R.N. D'Souza, J. D. Hartgerink “Sequence effects of self-assembling MultiDomain Peptide Hydrogels on encapsulated SHED cells” Biomacromolecules, 2014, 15, 2004-2011. DOI: 10.1021/bm500075r.
V. A. Kumar, N. L. Taylor, A. A. Jalan, L. K. Hwang, B. K. Wang, Jeffery D. Hartgerink “A Novel Synthetic Collagen Mimic for Hemostasis” Biomacromolecules 2014, 15, 1484−1490. DOI: 10.1021/bm500091e.
2013
A. A. Jalan, J. D. Hartgerink “Pairwise interactions in collagen and the design of heterotrimeric helices” Curr. Opin. Chem. Biol. 2013, 17, 6, 960–967. DOI: 10.1016/j.cbpa.2013.10.019.
A. A. Jalan, B. Demeler, J. D. Hartgerink “Hydroxyproline-Free Single Composition ABC Collagen Heterotrimer” J. Am. Chem. Soc. 2013, 135, 6014-6017. DOI: 10.1021/ja402187t.
E. L. Bakota, O. Sensoy, B. Ozgur, M. Sayar, and J. D. Hartgerink “Self-Assembling Multidomain Peptide Fibers with Aromatic Cores” Biomacromolecules 2013, 14, 1370–1378. DOI:10.1021/bm4000019.
A. A. Jalan and J. D. Hartgerink “Simultaneous Control of Composition and Register of an AAB-type Collagen Heterotrimer” Biomacromolecules 2013, 14, 179-185. DOI:10.1021/bm3015818.
2012
J. A. Fallas and J. D. Hartgerink “Computational Design of Self-Assembling Register-Specific Collagen Heterotrimers” Nat. Comm. 2012, 3, 1087. DOI:10.1038/ncomms2084.
F. Wei, J. Fallas and J. D. Hartgerink “Sequence Position and Side Chain Length Dependence of Charge Pair Interactions in Collagen Triple Helices” Macromol. Rapid. Comm. 2012, 33 (17) 1445-1452. DOI:10.1002/marc.201200221.
J. A. Fallas, J. Dong, Y. J. Tao and J. D. Hartgerink "Structural insights into charge pair interactions in triple helical collagen-like proteins" J. Biol. Chem. 2012, 287 (11) 8039-47. DOI: 10.1074/jbc.M111.296574.
J. A. Fallas, M. A. Lee, Abhishek A. Jalan, and J. D. Hartgerink "Rational Design of Single-Composition ABC Collagen Heterotrimers" J. Am. Chem. Soc. 2012, 134, 1430-1433. DOI: 10.1021/ja209669u.
K. M. Galler, Jeffrey D. Hartgerink, A. C. Cavender, G. Schmalz and R. N. D'Souza "A Customized Self-Assembling Peptide Hydrogel for Dental Pulp Tissue Engineering" Tissue Eng. A 2012, 13 (1-2) 176-184. DOI: 10.1089/ten.TEA.2011.0222.
2011
K. M. Galler, R. N. D'Souza, M. Federlin, A. C. Cavender, J. D. Hartgerink, S. Hecker, G. Schmalz “Dentin Conditioning Codetermines Cell Fate in Regenerative Endodontics” J. Endo. 2011, 37, 11, 1536-1541. DOI: 10.1016/j.joen.2011.08.027.
L. E. R. O’Leary, J. A. Fallas, E. L. Bakota, M. K. Kang and J. D. Hartgerink "Multi-hierarchical self-assembly of a collagen mimetic peptide from triple helix to nanofiber and hydrogel" Nature Chem. 2011, 3, 821-828. DOI:10.1038/nchem.1123.
W. C. Pomerantz, V. M. Yuwono, R. Drake, J. D. Hartgerink, N. L. Abbott and S. H. Gellman "Lyotropic Liquid Crystals Formed from ACHC-Rich β-Peptides" J. Am. Chem. Soc. 2011, 133 (34) 13604-13613. DOI: 10.1021/ja204874h.
K.M. Galler, R.N. D'Souza, J.D. Hartgerink, and G Schmalz "Scaffolds for Dental Pulp Tissue Engineering" Adv. Dent. Res. 2011, 23 333-339. DOI: 10.1177/0022034511405326.
E. L. Bakota, Y. Wang, F. R. Danesh, and J. D. Hartgerink "Injectable Multidomain Peptide Nanofiber Hydrogel as a Delivery Agent for Stem Cell Secretome" Biomacromolecules 2011, 12 1651-1657. DOI: 10.1021/bm200035r.
L. E. R O'Leary, J. A. Fallas and J. D. Hartgerink "Positive and Negative Design Leads to Compositional Control in AAB Collagen Heterotrimers" J. Am. Chem. Soc. 2011, 133, 5432-5443. DOI: 10.1021/ja111239r.
Y. Wang, E. Bakota, B. H. J. Chang, M. Entman, J. D. Hartgerink, and F. R. Danesh "Peptide Nanofibers Preconditioned with Stem Cell Secretome Are Renoprotective" J. Am. Soc. Nephrology. 2011, 22, 704-717. DOI: 10.1681/ASN.2010040403.
E. L. Bakota, L. Aulisa, K. M. Galler and J. D. Hartgerink "Enzymatic Cross-Linking of a Nanofibrous Peptide Hydrogel" Biomacromolecules 2011, 12, 82-87. DOI: 10.1021/bm1010195.
2010
K. M. Galler, R. N. D'Souza and J. D. Hartgerink “Biomaterials and their Potential Applications for Dental Tissue Engineering” J. Mater. Chem. 2010, 20, 8730-8746. DOI: 10.1039/C0JM01207F.
J. A. Fallas, L. E. R. O’Leary and J. D. Hartgerink “Synthetic collagen mimics: self-assembly of homotrimers, heterotrimers and higher order structures” Chem. Soc. Rev. 2010, 39, 3510-3527. DOI: 10.1039/B919455J.
K. M. Galler, L. Aulisa, K. R. Regan, R. N. D'Souza and J. D. Hartgerink "Self-assembling Multidomain Peptide Hydrogels: Designed Susceptibility to Enzymatic Cleavage Allows Enhanced Cell Migration and Spreading" J. Am. Chem. Soc. 2010, 132 (9) 3217-3223. DOI: 10.1021/ja910481t.
L. Russell, J. Fallas and J. D. Hartgerink “Selective Assembly of a High Stability AAB Collagen Heterotrimer” J. Am. Chem. Soc. 2010, 132 (10) 3242-3243. DOI: 10.1021/ja909720g.
2009
J. Fallas, V. Gauba, J. D. Hartgerink "Solution structure of an ABC collagen heterotrimer reveals a single-register helix stabilized by electrostatic interactions" J. Biol. Chem. 2009, 284, 26851-26859. DOI: 10.1074/jbc.M109.014753.
L. Aulisa, H. Dong, J. D. Hartgerink "Self-Assembly of Multidomain Peptides: Sequence Variation Allows Control over Cross-Linking and Viscoelasticity" Biomacromolecules 2009, 10 (9) 2694-2698. DOI: 10.1021/bm900634x.
E. Bakota, L. Aulisa, D. Tsyboulski, B. R. Weisman, J. D. Hartgerink "Multidomain Peptides as Single-Walled Carbon Nanotube Surfactants in Cell Culture" Biomacromolecules 2009, 10 (8) 2201-2206. DOI: 10.1021/bm900382a.
D. Zhang, O. Neumann, H. Wang, V. M. Yuwono, A. Barhoumi, M. Perham, J. D. Hartgerink, P. Wittung-Stafshede, N. J. Halas "Gold Nanoparticles Can Induce the Formation of Protein-based Aggregates at Physiological pH" Nano Lett. 2009, 9 (2) 666-671. DOI: 10.1021/nl803054h.
L. Aulisa, N. Forraz, C. McGuckin, J. D. Hartgerink "Inhibition of Cancer Cell Proliferation by Designed Peptide-Amphiphiles" Acta Biomaterialia 2009, 5, 842-853. DOI: 10.1016/j.actbio.2008.11.002.
2008
H. Dong, V. M. Yuwono and J. D. Hartgerink “Supramolecular Polymerization of Peptides and Peptide Derivatives: Nanofibrous Materials.” In Molecular Recognition and Polymers (eds V.M. Rotello and S. Thayumanavan) 2008. DOI: 10.1002/9780470384053.ch14
C. L. Pizzey, W. C. Pomerantz, B.-J. Sung, V. M. Yuwono, S. H. Gellman, J. D. Hartgerink, A. Yethiraj, and Nicholas L. Abbott "Characterization of nanofibers formed by self-assembly of beta-peptide oligomers using small angle x-ray scattering" J. Chem. Phys. 2008, 129, 095103.
D. Tsyboulski, E. Bakota, L. Witus, J-D. Rocha, J. D. Hartgerink, B. R. Weisman "Self-Assembling Peptide Coatings Designed for Highly Luminescent Suspensions of Single-Walled Carbon Nanotubes" J. Am. Chem. Soc. 2008, 130, 17134-17140.
H. Dong, S. E. Paramonov and J. D. Hartgerink "Self-assembly of alpha-helical coiled-coil nanofibers" J. Am. Chem. Soc. 2008, 130, 13691-13695.
K. M. Galler, A. Cavender, V. Yuwono, H. Dong, S. Shi, G. Schmalz, J. D. Hartgerink and R. N. D'Souza "Self-Assembling Peptide Amphiphile Nanofibers as a Scaffold for Dental Stem Cells" Tissue Eng. 2008, 14 (12) 2051-2058.
F. Wei, D. Zhang, N. J. Halas and J. D. Hartgerink "Aromatic amino acids provide characteristic motifs in the Raman and SERS spectroscopy of Peptides" J. Phys. Chem., 2008, 113, 9158-9164.
V. Gauba and J. D. Hartgerink "Synthetic Collagen Heterotrimers: Structural Mimics of Wild Type and Mutant Collagen Type I" J. Am. Chem. Soc. 2008, 130, 7509-7515. (Highlighted in Nature "News & Views" 2008, 453 998-999.)
W. C. Pomerantz, V. M. Yuwono, C. L. Pizzey, J. D. Hartgerink, N. L. Abbott and S. H. Gellman “Nanofibers and Lyotropic Liquid Crystals from a New Class of Self-Assembling Beta-Peptides” Angew. Chem. 2008, 47, 1241-1244.
H-W. Jun, S. E. Paramonov, H. Dong, N. Forraz, C. McGuckin, and J. D. Hartgerink "Tuning the mechanical and bioresponsive properties of peptide-amphiphile nanofiber networks" J. Biomater. Sci. Polymer Edn. 2008, 19, 665-676.
2007
V. Gauba and J. D. Hartgerink “Surprisingly High Stability of Collagen ABC Heterotrimer: Evaluation of Side Chain Charge Pairs” J. Am. Chem. Soc. 2007, 129, 15034-15041. DOI: 10.1021/ja075854z.
H. Dong, S. E. Paramonov, L. Aulisa, E. L. Bakota and J. D. Hartgerink “Self-assembly of Multi-domain Peptides: Balancing Molecular Frustration Controls Conformation and Nanostructure” J. Am. Chem. Soc. 2007, 129, 12468-12472. DOI: 10.1021/ja072536r.
M. B. Murphy, J. D. Hartgerink, A. Goepferich, and A. G. Mikos, “Synthesis and In Vitro Hydroxyapatite Binding of Peptides Conjugated to Calcium-Binding Moieties” Biomacromolecules 2007, 8, 2237-2243. DOI: 10.1021/bm070121s.
L. S. Witus, J-D. R. Rocha, V. M. Yuwono, S. E. Paramonov, R. B. Weisman, J. D. Hartgerink “Peptides that noncovalently functionalize single-walled carbon nanotubes to give controlled solubility characteristics” J. Mater. Chem. 2007, 17, 1909-1915. DOI: 10.1039/B700174F.
V. M. Yuwono and J. D. Hartgerink “Peptide amphiphile nanofibers template and catalyze silica nanotube formation” Langmuir 2007, 23, 5033-5038. DOI: 10.1021/la0629835.
V. Gauba and J. D. Hartgerink “Self-Assembled heterotrimeric collagen triple helices directed through electrostatic interactions” J. Am. Chem. Soc. 2007, 129, 2683-2690. DOI: 10.1021/ja0683640.
H. Dong and J. D. Hartgerink “The role of hydrophobic clusters in the stability of alpha-helical coiled coils and their conversion to amyloid-like beta-sheets” Biomacromolecules 2007, 8, 617-623. DOI: 10.1021/bm060871m.
J. Yang, L. B. Alemany, J. Driver, J. D. Hartgerink, A. R. Barron “Fullerene-derivatized amino acids: Synthesis, characterization, antioxidant properties, and solid-phase peptide synthesis” Chem. Eur. J. 2007, 13, 2530-2545. DOI: 10.1002/chem.200601186.
V. Gauba and J. D. Hartgerink “Recent Advances in Supramolecular Polymers” Physical Properties of Polymers Handbook, 2nd Ed. James E. Mark, Ed. Springer, 2007, 715-722. DOI: 10.1007/978-0-387-69002-5_45.
2006
C. McGuckin, N. Forraz, M-O. Baradez, C. Basford, A. M. Dickinson, S. Navran, J. D. Hartgerink “Embryonic-like stem cells from umbilical cord blood and potential for neural modeling” Acta Neurobiol. Exp. 2006, 66, 321-329. DOI: 10.55782/ane-2006-1621.
J. D. Hartgerink “Nanomedicine: New material stops bleeding in a hurry” Nat. Nanotechnol. 2006, 1, 166-167. DOI: 10.1038/nnano.2006.148.
C. S. Levin, B. G. Janesko, R. Bardhan, G. E. Scuseria, J. D. Hartgerink, N. J. Halas “Chain-length-dependent vibrational resonances in alkanethiol self-assembled monolayers observed on plasmonic nanoparticle substrates” Nano Lett. 2006, 6, 2617-2621. DOI: 10.1021/nl062283k.
S. E. Paramonov, H. W. Jun, J. D. Hartgerink “Self-assembly of peptide-amphiphile nanofibers: the roles of hydrogen bonding and amphiphilic packing” J. Am. Chem. Soc. 2006, 128, 7291-7298. DOI: 10.1021/ja060573x.
H. Dong, J. D. Hartgerink “Short homodimeric and heterodimeric coiled coils” Biomacromolecules 2006, 7, 691-695. DOI: 10.1021/bm050833n.
H. W. Jun, S. E. Paramonov, J. D. Hartgerink “Biomimetic self-assembled nanofibers” Soft Matter 2006, 2, 177-181. DOI: 10.1039/B516805H.
M. J. Pender, L. A. Sowards, J. D. Hartgerink, M. O. Stone, R. R. Naik “Peptide-mediated formation of single-wall carbon nanotube composites” Nano Lett. 2006, 6, 40-44. DOI: 10.1021/nl051899r.
S. E. Paramonov, H. W. Jun, J. D. Hartgerink “Modulation of peptide-amphiphile nanofibers via phospholipid inclusions” Biomacromolecules 2006, 7, 24-26. DOI: 10.1021/bm050798k.
2005
H. W. Jun, V. Yuwono, S. E. Paramonov, J. D. Hartgerink “Enzyme mediated degradation of peptide-amphiphile nanofiber networks” Adv. Mater. 2005, 17, 2612-2617. DOI: 10.1002/adma.200500855.
S. E. Paramonov, V. Gauba, J. D. Hartgerink “Synthesis of collagen-like peptide polymers via native chemical ligation” Macromolecules 2005, 38, 7555-7561. DOI: 10.1021/ma0514065.
S. E. Paramonov, J. D. Hartgerink “Nanostructured Collagen Mimics in Tissue Engineering” Nanofabrication Towards Biomedical Applications, C. Kumar, J. Hormes, C. Leuschner, Eds. Wiley, 2005, 95-117. Link to book. Direct link to article PDF.
2004
J. D. Hartgerink “Covalent capture: A natural compliment to self-assembly” Curr. Opin. Chem. Biol. 2004, 8, 604-609. DOI: 10.1016/j.cbpa.2004.10.001.
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